160 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... phosphate crystals #TumorLysis ... #syndrome #TLS ... #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Hyperkalemia #TumorLysis ... #Syndrome #TLS ... #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... gluconate #TumorLysis ... #Syndrome #TLS ... #diagnosis #management
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Aldosterone: Liddle's Syndrome ... SAME, Cushing Syndrome ... Renin secreting tumor ... diuretics, Bartter syndrome ... , Gitelman syndrom
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal Syndromes ... and Mimics - Differential ... Antiphospholipid Syndrome ... differentiation syndrome ... Pulmonary #Renal #Syndromes
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Irritable Bowel Syndrome ... (IBS) - Pathophysiology ... Diagnosis and Management ... functional somatic syndromes ... Irritable #Bowel #Syndrome
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Virilization - Differential ... Polycystic Ovarian Syndrome ... • Cushing's Syndrome ... Insulin Resistance Syndrome ... Paraneoplastic Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... hyperviscosity syndrome ... Lysis Syndrome: ... #Lysis #Syndrome ... TLS #diagnosis #management
Tall Stature - Differential Diagnosis Algorithm

Normal Growth (BA=CA)
 • Familial Tall Stature
 • XYY Syndrome
Obese BMI
Stature • XYY Syndrome ... Klinefelter's Syndrome ... • Soto's Syndrome ... Bechwith-Weidmann Syndrome ... • XYY Syndrome
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Diuretics, Bartter Syndrome ... , Gitelman Syndrome ... Renin-secreting tumor ... GRA, Cushing's syndrome ... , Liddle syndrome