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differential management symptoms erythematosus lupus sle systemic thrombocytosis activation anemias antinxp2 antinxp2dm aplastic arteritis autoantibodies autoimmune cancer causes chronic cll
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Algorithm Signs ... #Differential #Diagnosis ... #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... effect following treatment ... Iron deficiency anemia ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management ... #treatment #hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... , Shaw sign, holster ... sign, and Gottron's ... after 2 years of treatment ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Erythematosus - Diagnosis ... 69% - Malar rash ... - Hemolytic anemia ... autoantibodies #signs ... #differential #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... present, symptoms, signs ... • Treatment algorithms ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
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