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differential causes erythematosus sle management oncology workup arthritis criteria hemolytic signs symptoms testing activation arthritides autoantibodies bleeding bruising cardiology chronic
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia ... #Lupus #SLE #systemic ... signs #symptoms #diagnosis ... #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... NEUROLOGIC - HEMOLYTIC ANEMIA ... (<1000/MM3) - THROMBOCYTOPENIA ... #Diagnosis #Rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Hematology
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
- Differential Diagnosis ... Lupus Erythematous ... Undifferentiated UCSD ... #Differential #Diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... - Hemolytic anemia ... Lupusreference #SLE #Systemic ... #differential #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... pericarditis • Hematologic ... domain: Leukopenia, Thrombocytopenia ... Criteria #SLE #Systemic ... #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Algorithm Decreased ... Megakaryopoiesis • Aplastic Anemia ... #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... deficiency • Fanconi’s anemia ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Algorithm Reactive ... • Systemic ... Lupus Erythematosus ... #Hematology #Oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... , and thrombocytopenia ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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