1160 results
diagnosis clinical cardiology management radiology differential symptoms signs mri nephrology algorithm msk syndrome pharmacology endocrinology causes neurology cardiacmri ophthalmology treatment
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
syndrome (TLS) - Pathophysiology ... phosphate, and uric ... deposition of uric ... syndrome #TLS #Pathophysiology
Uric Acid Homeostasis In the liver, purines are metabolized to uric acid. The last step in purine
Uric Acid Homeostasis ... metabolized to uric ... uricase converts uric ... 3 of the daily uric ... Homeostasis #Gout #Pathophysiology
Role of Uric Acid in the Inflammation of Gout Allopurinol, Febuxostat - Xanthine oxidase Colchicine - Release of
Role of Uric Acid ... gout #uricacid #pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... / Xanthine -> Uric ... Syndrome #TLS #Pathophysiology
Gout: Pathogenesis and Clinical Findings - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders -
acid compete with uric ... , excretion of uric ... acid -> Incr uric ... into joints -> Uric ... Hyperuricemia #Pathophysiology
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
kidneys to filter uric ... Decr secretion of uric ... Under-excretion of Uric ... abnormally high uric ... Hyperuricemia #Pathophysiology
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Syndrome (TLS) Pathophysiology ... Ca, ↑K, ↑LDH, ↑Uric ... Syndrome #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... phos, Elevated uric
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
bases, including uric ... Segments #Function #Pathophysiology
Allopurinol Pharmacology Summary Xanthine oxidase inhibitor blocking the formation of new uric acid Initiate 1-2 days prior to
formation of new uric ... of pre-formed uric ... #Pharmacology #pathophysiology
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