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diagnosis management differential erythematosus hematology neurology systemic classification druginduced hemophagocytic hlh lymphohistiocytosis oncology signs symptoms vasculitis workup acromegaly activation anca
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management ... Summary • Epidemiology ... Positive in 60-80% of cases ... life-threatening • Treatment ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... (ANA) - 95% - Initial ... severe disease Treatment ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... vasculopathy, thrombosis and ... (@neudrawlogy) and
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
demineralization, and ... Osteonecrosis Esp. humeral and ... Myopathy (Also caused ... #MSK #Musculoskeletal ... Complications #pathophysiology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
with PTU (50%) and ... Discontinuation of causal ... Hydroxychloroquine, csDMARDs and ... weeks to months) and ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... pain • Swan neck/Ulnar ... SSA can rule in SLE ... Erythematosus #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... (RA), Systemic lupus ... erythematosus (SLE ... MD @MithuRheu and ... Differential #Diagnosis #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... MD) - Diagnosis and ... Management Summary ... old, ~10,000 new cases ... for diagnosis and
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... ) • Systemic lupus ... in drug-induced SLE ... • Sjögren syndrome ... • Polymyositis and
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... temperatures below 37°C and ... endothelial injury and ... neuropathy, arthralgia, and ... ) • Types II and
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