54 results
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... cases are caused ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... colored compounds (e.g ... #nephrology #interpretation ... #diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... but in severe cases ... May be 10 (eg direct ... #Proteinuria #Nephrology ... #Diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... osmolarity If cause ... • Cardio-renal syndrome ... #nephrology #causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... • Hepatorenal syndromes ... Epithelial cell casts ... #Nephrology #Differential ... #Causes
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sensitive) • AKI ... sterile pyuria, WBC casts ... proteinuria, granular casts ... AIN #Algorithm #nephrology ... #diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology ... #Diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... proteinuria, RBC casts ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Pain/Post-op • Neurologic ... • Reduced GFR, AKI ... Hypo-osmolar urine ... Uosm < 100 mmol/kg ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Pain/Post-op • Neurologic ... • Reduced GFR, AKI ... Hypo-osmolar urine ... Uosm < 100 mmol/kg ... #Hyponatremia #Nephrology