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algorithm differential acute aki proteinuria workup glomerular kidneyinjury microscopy nephrotic biopsy blood classification diseases glomerulonephritis hematuria indications injury interpretation lupus
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... acute and chronic kidney ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... proteinuria, RBC casts ... → Refer to Nephrology ... if cause not identified ... by UW IM Residency
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Approach to Acute Kidney ... PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... #nephrology
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... and concentrated urine ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... sediment - WBC/RBC casts ... proliferative • Anti-GBM ... #Proteinuria #Nephrology ... #Differential #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
syndrome—due to GBM ... RBC casts in urine ... but in severe cases ... #Proteinuria #Nephrology ... #Diagnosis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... - Differential Diagnosis ... Algorithm Acute Kidney ... Epithelial cell casts ... #KidneyInjury #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential Diagnosis ... osmolarity If cause ... ANCA, ANA, Anti-GBM ... #nephrology #causes
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis - Diagnostic ... • Nephritic urine ... dysmorphic RBCs, RBC casts ... , WBC casts) especially ... algorithm #sle #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
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