29 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... bcr-able (+) ↑ WBC
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Blood Loss ... • Acute Bleed - ... • Anemia of Chronic
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Diagnosis Algorithm ... Fatigue • Acute ... Age > 50 • Chronic ... #Causes #Hematology ... #Oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... Index > 3: • Acute ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... Infectious: • Acute ... Iron deficiency anemia ... #Causes #Hematology
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... Disorders • Acute ... ) • Acute ... - Hemolytic Anemia
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... ’s lymphoma or acute ... diagnosis #workup #oncology