53 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... RA, SLE, PRV, Chronic ... Normal/lncreased WBCs ... Normal RBCs • Acute ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Malignant tumors, Acute ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... disease, Acute ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... deficiencies: Chronic ... Index > 3: • Acute ... Production #Index #hematology ... #diagnosis #calculation
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... Iron deficiency anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential Diagnosis ... Thrombocytosis): • Acute ... malignancies • Anemia ... Myelodysplastic syndrome ... #Causes #hematology
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Causes of Chronic ... - Differential Diagnosis ... Stable Angina • Acute ... Coronary Syndrome ... - Other • Anemia
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Algorithm Acute ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC