36 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Diagnosis Algorithm ... #Anemias #Differential ... #Diagnosis #Algorithm ... #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... anemia" • HELLP ... syndrome • Catastrophic ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... TTP, HUS, DIC, HELLP ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Bleed • Hemolysis ... #Diagnosis #Algorithm ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Diagnosis Algorithm ... Initial Workup: CBC ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #hematology #workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... syndrome - ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... Diagnosis Algorithm ... elliptocytosis - RBC ... #Diagnosis #Algorithm ... #Causes #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS, HELLP ... Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... (Hemolysis, Elevated ... AFLP #obstetrics #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... thrombocytopenia - DIC, TTP, HELLP ... #Anemia #Differential ... #workup #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Non-megaloblastic: Liver ... #Differential # ... Diagnosis #hematology