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differential algorithm anemia management oncology causes workup comparison hemolysis intravascular aflp atlas blood chronic cll extravascular hellp lymphocytic microscopy monoclonal
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential #Diagnosis ... #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Bleed • Hemolysis ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... Algorithm #Causes #Hematology
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... X 1010); some WBC ... X 1011); some WBC ... Contents #Volume #Hematology ... #Management #Table
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... (Pancytopenia, WBC ... (CBC with Lymphocytes ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... platelets, persistent WBC ... #Algorithm #hematology ... #WBC #Leukemoid
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... Asplenism, Severe hemolytic ... Sickle cell, MDS #RBC ... Inclusions #Bodies #diagnosis ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... 2) External (RBC ... 3) Internal (RBC ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... - Differential Diagnosis ... elliptocytosis - RBC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... #differential #diagnosis ... #hematology #microscopy
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