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diagnosis hematology management causes algorithm neurology anemia kidney kidneyinjury leukemia renal workup apml autoimmune blood calcium calculation cauda caudaequina classification
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
sinusoidal obstructive syndrome ... Capillary leak syndrome ... • Tumor lysis syndrome ... #Cancer #Oncology ... #Differential #
Hypophosphatemia - Differential Diagnosis Algorithm Appropriately Low Kidney Phosphate Excretion: • Decreased GI Absorption: Chronic Diarrhea, Antacids,
GI Absorption: Chronic ... Shift: Refeeding Syndrome ... , Acute Respiratory ... Tumor Genesis Syndrome ... FGF23: Fanconi Syndrome
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Syndrome - Diagnosis ... adsorption onto cancer ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Hyperviscosity Syndrome ... Leukostasis: • WBC ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome ... diagnosis #cancer
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... ) - Differential ... • Hepatorenal syndromes ... Constipation • Prostate Cancer ... #Nephrology #Differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI ... - Differential ... inhibitors, hepatorenal syndrome ... fibrosis, cervical cancer ... #Diagnosis #nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... fever - ACS, AKI ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... Differentiation #Syndrome ... #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g. cancer ... • "Hospital-acquired ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential
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