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Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Tolvaptan #Diuretics ... #Medications #Pharmacology ... #summary #table ... #nephrology
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... abnormalities - Hypercalcemia ... - Hypokalemia ... Hypomagnesemia #Differential ... Low #Magnesium #Table
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure • Furosemide •
commonly used diuretics ... medications in ... Spironolactone MCW Nephrology ... #pharmacology # ... halflife #comparison #table
Compelling and Possible Contraindications to Antihypertensive Drugs Diuretics (thiazides) - Gout - Metabolic syndrome, Glucose intolerance, Pregnancy,
Antihypertensive Drugs Diuretics ... ARB, diabetes) ACE ... failure - Co-medication ... antihypertensive #medications ... contraindications #table
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... MunerMohamed1 #hyperkalemia ... #differential # ... pathophysiology #pharmacology ... #potassium #medications
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... >20 mEq/24 h - Diuretics ... Gitelman's syndrome #Hypokalemia ... #Differential # ... Diagnosis #Algorithm #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Thyrotoxicosis Medications ... • Discontinued diuretic ... #Differential # ... Diagnosis #Algorithm #nephrology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... hypomagnesemia #Medications ... #differential # ... diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... Inhibitors of Na+K+2Cl ... Hyponatremia • Hypercalcemia ... #Nephrology #Pharmacology ... #Medications #Table
Hypomagnesemia - Differential Diagnosis Renal Causes of Hypomagnesemia - Familial: Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Hypomagnesemia - Differential ... Hypomagnesemia - Acquired: Medications ... pentamidine), Hypercalcemia ... renal transplant, Diuretic ... diagnosis #causes #nephrology
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