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diagnosis hematology differential liver management algorithm anemia autoimmune hemolytic interpretation transaminitis workup acid aiha chemistry cold comparison criticalcare deficiency dosing
Massive Hemoptysis - Diagnosis and Management • Definitions: - Hemoptysis = bleeding from
Massive Hemoptysis ... Definitions: - Hemoptysis ... cords - Pseudo-hemoptysis ... cause death by asphyxia ... Diagnosis #Management #treatment
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Cold Autoimmune Hemolytic ... Spherocytes • Treatment ... Mostly transient hemolysis ... • Treatment: Warm ... #Anemia #hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA #Treatment ... #management #hematology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
2-5x normal - Hemolysis ... Liver #Injury #hepatology ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... Gilbert's syndrome • Hemolysis ... #differential #Hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... Overproduction (hemolysis ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Post-partum, ICH/TBI, Hemoptysis ... #Indications #Pharmacology ... #hematology
Nebulized Tranexamic Acid for acute treatment of stable hemoptysis - Mike O'Brien @MikeEMPharmD #Pharmacology #EBM #Management #Dosing #Pathophys
Acid for acute treatment ... of stable hemoptysis ... MikeEMPharmD #Pharmacology ... TranexamicAcid #Hemoptysis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
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