45 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... ): • Limited cutaneous ... thickening Signs and Symptoms ... interstitial lung disease ... diagnosis #signs #symptoms
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... most frequent skin ... appearing during the disease ... #oncology #clinical ... #skin
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... Extravascular lg Deposits: Systemic ... Cold agglutinin disease ... manifestations #dermatology ... #skin #clinical
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Raised off of the skin ... Blistering and/or skin ... Drug #Reactions #dermatology ... #clinical #comparison
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Most common extra cutaneous ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... nemaline myopathy Cutaneous-centered ... Ig deposition disease ... Differential #Diagnosis #hematology ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... : GI, neuro, cutaneous ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... vasculitis) • Cutaneous ... oral ulcers in 12 ... Arthritis, AS Treatment ... #rheumatology #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Arthralgia/arthritis, Skin ... solid cancers • Systemic ... diagnosis #management #treatment ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Neurological 12% ... Drug-induced lupus, Cutaneous ... autoantibodies #signs #symptoms ... #differential #rheumatology