33 results
diagnosis differential algorithm rheumatology oncology classification sle syndrome autoimmune cirrhosis erythematosus hepatopulmonary intravascular macrocytic mcv product reactions systemic activation aiha
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology ... #anemia
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
AIHA • Anemia ... type ± C3d • Blood ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Macrocytic RBC: Vitamin B12 ... , McLeod blood group ... Microangiopathic Hemolytic ... differential #diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... : • Systemic lupus ... Antibody-mediated hemolysis ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... (>100 fL) • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Anemia (AIHA) Treatment ... esp if severe disease ... #Anemia #AIHA # ... Treatment #management ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... • Pancreatic Disease ... • Liver Disease ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
loss), Vitamin B12 ... Chronic kidney disease ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... , deficiency anemia ... Diagnosis #Algorithm #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... PRODUCTION • Vitamin B12 ... RETIC INDEX: • Blood ... anemia, Hemolysis ... Differential #Diagnosis #Hepatology
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