31 results
hematology management algorithm causes classification leukemia signs symptoms syndrome workup chronic disorders erythematosus lupus lymphocytic systemic thrombocytopenia acidosis acute aortitis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Macrocytic RBC: Vitamin B12 ... iron deficiency anemia ... RBC #Morphology #differential ... #diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 ... deficiency • Fanconi’s anemia ... telomeropathy Cancer ... consumption • Vitamin B12 ... #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... • CLL • APLA ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... lymphoid organs When Cancer ... lymphocytic lymphoma (SLL ... #Oncology #Diagnosis
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Diagnosis Infectious ... Non-Infectious: • Rheumatologic ... : SLE, Rheumatoid ... • Metabolic: Uremia ... #cardiology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... non-Hodgkin lymphoma SLL ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
loss), Vitamin B12 ... Chronic kidney disease ... infiltration (e.g. cancer ... #anemia #differential ... #diagnosis #calculation
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... Radiation induced disease ... - Cytopenias (anemia ... #diagnosis #oncology ... #cancer #malignancy
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Diagnosis Framework ... erythematosus (SLE ... Other Causes: Cancer ... #Diagnosis #rheumatology
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