27 results
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... during an allergic reaction ... Or Inflammatory Reactions ... #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
fever, joint pain, bleeding ... night sweats, bleeding ... Petechiae, bruising, bleeding ... #Hematology #Oncology ... #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... - History of Bleeding ... Reed-Sternberg Cells ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... B-symptoms, bruising/bleeding ... predominant immature cells ... #Algorithm #hematology ... #WBC #Leukemoid
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... to MDS or acute leukemia ... #management #treatment ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... transformation to acute leukemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... : 33% • Treatment ... , and CXR with pulmonary ... #hematology #diagnosis ... #comparison #table
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... or basket cells ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... #oncology #hematology ... #hemeonc #diagnosis