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management differential oncology algorithm causes syndrome rheumatology workup classification clinical comparison leukemia photo acquired activetb aplastic blood chronic cll deficiency
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... , Bleeding gastric ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... neutropenia • Mucosal bleeding ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #treatment #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... predominant immature cells ... #Algorithm #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... 80-100 fL) • Bleeding ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... common inherited bleeding ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... #Algorithm #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... • Pancreatic Disease ... Macrocytosis, Target Cells ... • Liver Disease ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... by a hemophilia treatment ... #Management #treatment ... #hematology
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