20 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Early diagnosis ... prevent lethal cardiac ... complications. ... Disease #Features #Signs ... #Symptoms #Diagnosis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Signs / Symptoms ... / Complications ... seizures) - Cardiac ... pathophysiology #immunology #diagnosis ... #signs #symptoms
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Subcutaneous nodules, lupus ... pernio • Cardiac ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
to myosin and cardiac ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
30%; can be only symptom ... 3-12% • Cardiac ... incr in 27-75% • PCT ... 28% -> Incr risk complications ... Evaluation #Guide #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... 5% of patients Cardiac ... Cytopenias • Cardiac ... : • Symptoms limited ... La, anti-Jo-1, SCL