15 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Hemolysis - Differential ... Diagnosis Algorithm ... #Differential #Diagnosis ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... for Hemolysis - Intravascular ... Causes Intravascular ... #Causes #differential ... #diagnosis #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura - Diagnostic ... Pathophysiology: ... pulmonary #Diagnosis ... #Dermatology #Rash ... Palpable #Algorithm #Differential
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
D-dimer Plasma ... age, which can cause ... #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Disseminated Intravascular ... • Elevated D-Dimer ... protein C and S Pathophysiology ... • PTT: ↑ • D-Dimer ... #Coagulation #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... • Disseminated Intravascular ... #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... IVIG infusion Intravascular ... Hemolytic #Anemia #Differential ... #Diagnosis #causes ... classification #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... Diagnosis Framework ... artery aneurysm: Causes ... - Disseminated intravascular ... #hematology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Pathophysiology: ... Causes: 1) Exfoliative ... #Dermatology #Rash ... Nikolsky #Algorithm #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... products or D-dimer ... reflection of intravascular ... WBC count and differential ... #Workup #Hematology