46 results
diagnosis differential management causes signs algorithm hypocalcemia oncology complications hematology nephrology pth secondary treatment diabetes genetics lowcalcium malignancy neurology pediatrics
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Pseudohyperparathyroidism, Renal ... histoplasmosis) • Milk (calcium ... )-alkali syndrome ... differential #diagnosis #calcium ... #high #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Primary Hyperparathyroidism • Adenoma • Hyperplasia • MEN 1 and 2A Tertiary Hyperparathyroidism
Renal Failure, Post-Renal ... Autosomal Dominant Calcium ... Other • Excess Calcium ... Immobilization • Adrenal ... Diagnosis #Algorithm #Endocrinology
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
PTH) Effect in Calcium ... and Phosphorus Calcium ... - Net Effect Hypercalcemia ... #Phosphorus #pathophysiology ... #endocrinology
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... Lithium use • Calcium-sensing ... , adrenal, prostate ... • Milk-alkali syndrome ... #Causes #endocrinology
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Other humoral syndromes ... thyrotoxicosis, adrenal ... Differential #Diagnosis #Endocrinology
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 Hypercalcemia of Malignancy - Pathophysiology PTH-mediated • Parathyroid cancer • Ectopic production: Small cell lung cancer, ovarian
Hypercalcemia of ... Malignancy - Pathophysiology ... and intestinal calcium ... Mediated - Stimulate calcium ... @kdjhaveri #Hypercalcemia
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - ... Hypocalciuric Hypercalcemia ... Tumors: Lung, SCC, renal ... Bony Mets - Calcium ... Algorithm #causes #endocrinology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... 4.6 mg/dL • Calcium ... Intravenous fluids • Renal ... - Calcium gluconate ... #TumorLysis #Syndrome
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-OHD in the adrenal ... Signs/Symptoms/Complications ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... hydration - Hyperkalemia
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