37 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... transformation to acute ... leukemia Management ... Conservative/supportive care ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Presentation: Subacute-Acute ... : DAH, acute febrile ... , Anaphylaxis, Acute ... #management #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Fatigue • Acute ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #Oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... • Supportive care ... progress to MDS or acute ... #management #treatment ... #hematology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout Diagnosis ... medications • Acute ... • Colchicine: Acute ... #management #treatment ... #ULT #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... severity Treatment - Acute ... Chronic Management ... multidisciplinary care ... #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... granules which are ... translocation • Acute ... thrombocythemia • Acute ... #causes #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... ) Differential Diagnosis ... Support - Critical care ... Liver #Pregnancy #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... tumour B cells are ... Treated Like Acute ... pathophysiology #Hematology ... #Diagnosis #NonHodgkin
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
It is rare in presentation ... presents as an acute ... insulting agent are ... #management #treatment ... #hematology