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rheumatology systemic differential erythematosus management neurology pathophysiology autoantibodies autoimmune complications disease druginduced manifestations myopathy oncology table testing treatment vasculitis algorithm
Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... #diagnosis
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
(SLE) - Typical ... Signs/Symptoms ... Arthralgia / arthritis, Myositis ... #Signs #Symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Normal CK - Myositis ... pathophysiology #signs ... #symptoms #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
anemia 4% - Myositis ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... Can also see mechanics ... #diagnosis #rheumatology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Erythematosus #SLE ... pathophysiology #signs ... #symptoms #diagnosis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... glycoprotein I (ß2GP), Lupus ... LAC) • Sjogren Syndrome ... Peptide (CCP) • Myositis ... #diagnosis #associations
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
positive NMO only): Myositis ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
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