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algorithm testing ana antibody antinuclear management nuclear patterns adultonset anemia causes classification cytoplasmic disease diseases gap globulin hemolytic heon hodgkins
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Malignancy: Metastatic cancer ... Inflammatory Conditions: Rheumatologic ... #hematology
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
rhythm monitoring, Echocardiogram ... Age-appropriate cancer ... - No other workup ... #hematology #diagnosis ... #algorithm #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... hemopathies, solid cancers ... Complications: MAS ... management #treatment #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... genotypes): SS, SC ... #Diagnosis #Algorithm ... #workup #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
, PM/SSc OS, MCTD ... , PBC/SSc OS ... phenomenon, SjS, cancer ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
helminthiasis, cancer ... Myelogram/BM biopsy (Mast ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology ... #Workup
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Anterior mediastinal mass ... Hodgkin Lymphoma Workup ... X-ray (Mediastinal mass ... Immunohistochemical studies (to differentiate ... classification #hematology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
, PM/SSc OS, MCTD ... , PBC/SSc OS • ... phenomenon, SjS, cancer ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Subglottic stenoses (SGS) during systemic diseases Subglottic stenosis (SGS) = congenital (children) or acquired (adult) characterized by
Work-up: • Biology ... Laryngotracheal cancer ... systemic #diseases #differential ... #diagnosis #causes ... #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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