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diagnosis causes hematology algorithm medications neurology aki hemolytic injury kidney rheumatology seizures table acidosis approach calculation ck compared comparison creatine
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... in Hemolytic Anemia ... #medications #Hemolytic ... #Anemia #differential ... #diagnosis #pharmacology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Deficiency • Drugs ... #MCV #Classification ... #Differential # ... Algorithm #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Blood Loss • Acute ... #Classification ... #Approach #Differential ... Algorithm #Causes #Hematology
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... Acute Kidney Injury ... decongestants) • Any drug ... #Drugs #pharmacology ... #differential #
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... AIHA: warm, cold, drug ... Diagnosis #causes #classification ... #hematology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... (AKI) - Differential ... Congestion • Medications ... Infection-mediated, Drug-induced ... #Diagnosis #nephrology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... • Reaction to Medications ... Thrombocytosis #Platelets #Differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Index < 2: • Anemia ... suppression (e.g. drugs ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... delayed HTR • Drug-induced ... immune-complex hemolytic anemia ... • Acute HTR ... Algorithm #Causes #Hematology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
of Seizures - Differential ... Toxic: Alcohol, Medication ... , Recreational drugs ... Cerebral Hypoxia, Uremia ... Algorithm #Causes #neurology
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