10 results
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
Retroviral Infections ... Mechanisms of Oncogenesis ... Note: A retrovirus ... /leukemia) #Retroviral ... #oncogenesis #pathophysiology
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral ... Syndrome Acute Retroviral ... infection Acute Retroviral ... #Acute #Retroviral
Acute Pharyngitis: Differential Diagnosis
Infectious:
 • Respiratory viruses (25-45%)
 • Group A Strep (5-15%)
 • Other bacteria:
• STDs: Acute Retroviral
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
that activate oncogenes
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Acetaminophen, Anti-retroviral
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Colchicine, Anti-retrovirals
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
expression of proto-oncogenes
The protein complex mTORC1 is a convergence point for multiple signaling pathways that control cell growth
network are many oncogenes ... Pathophys #mTOR #oncogenes
Medications Contributing to Dysgeusia

Antimicrobial medicines	Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
inhibitors (PPI) Anti-retroviral
Human Immunodeficiency Virus (HIV)
HIV is a double stranded RNA retrovirus (retro refers to reverse transcriptase).
It binds
double stranded RNA retrovirus