13 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... phenomenon, SjS, cancer ... ARUPLabs #ANA #Antinuclear ... #differential #diagnosis ... #rheumatology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... - Differential Diagnosis ... , Breast) • Cancer ... Epitrochlear (Always pathologic ... #Hematology #Oncology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... phenomenon, SjS, cancer ... ARUPLabs #ANA #Antinuclear ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... , Polymyositis/Dermatomyositis ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology # ... dermatology #diagnosis
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... Associated Features: Cancer-associated ... heliotrope, shawl sign ... #differential #diagnosis ... #comparison #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Causes: - Idiopathic ... , breast CA - Hematologic ... multiforme - Dermatomyositis ... #dermatology #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... helminthiasis, cancer ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology