22 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Tests - Prolonged PT ... and Prolonged PT ... Abnormal #APTT #Laboratory ... #Hematology #Diagnosis
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
• Elevation in thrombin ... platelet aggregation PT ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... Clotting Time, Thrombin ... Anticoagulation #Testing #Diagnosis ... #Laboratory #Effects
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time (PT ... Prothrombin Time (PT ... thematttsai #PT ... Thromboplastin #laboratory ... #hematology #diagnosis
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Heparin, or Direct Thrombin ... Prolonging the PT ... APTT #prolonged #diagnosis ... #hematology #evaluation
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... 2B) • Normal PT ... VonWillebrand #Disease #Diagnosis ... #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
- Differential Diagnosis ... 12-13 g/dL, • ANC ... iron studies, PT ... Differential Diagnosis ... #Algorithm #hematology
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
FVa to generate thrombin ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory