1522 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... cell lysis → Release ... #TumorLysis #syndrome
Carpal Tunnel Syndrome: Pathogenesis and clinical findings
 • Dysthesias - Tingling, burning, or painful sensation at
Carpal Tunnel Syndrome ... Carpal Tunnel Release ... #CarpalTunnel #Syndrome
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
of Tumor Lysis Syndrome ... Cell Lysis -> Release ... #TumorLysis #Syndrome
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Adenosine release ... #cardiorenal #syndrome
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Oxitriptan ↑ Serotonin Release ... ucsdim #Serotonin #Syndrome
Airway Pressure Release Ventilation (APRV) - Early application of airway pressure release ventilation may reduce the
Airway Pressure Release ... airway pressure release ... respiratory distress syndrome
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... Withdrawal seizure, relapse
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... leading to the release
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Cardiorenal Syndrome ... dysfunction, cytokine release ... #Cardiorenal #Syndrome
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... : • Cytokine Release ... • Cathepsin G release ... Differentiation #Syndrome