58 results
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Inflammation of Gout ... inflammation #gout ... #uricacid #pathophysiology ... #pharmacology #rheumatology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout ... 1) 2+ flares/year ... 2) Gouty tophi ... NUIM_Chiefs #gout ... treatment #ULT #rheumatology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
injury -> Ligaments tear ... Inability to weight-bear ... msk #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
II: Incomplete tear ... Ill: Complete tear ... #Sports #MSK #orthopedics ... Grades #Diagnosis #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... Posterior Cord Syndrome ... #diagnosis #pathophysiology ... symptoms #msk #orthopedics
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Monoarticular • Gout ... -4 joints) • Gout ... Sicca) Syndrome ... Diagnosis #Algorithm #Orthopedics
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Nodules • RA • Gout ... Tophi - Gout ... GI - Felty syndrome ... Inflammation of ear ... differential #diagnosis #rheumatology
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
loading compresses/tears ... pulposus extrudes out ... through these tears ... complications #msk #pathophysiology
Lemierre’s Syndrome - Pathophysiology

Lemierre’s is an infectious thrombophlebitis of the internal jugular vein.

 - It starts
Lemierre’s Syndrome ... - Pathophysiology ... - It starts out ... #Lemierres #Syndrome ... #Pathophysiology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... Sjögren's, the syndrome ... - Decreased tear ... Primary #Sjogrens #Syndrome ... #Pathophysiology