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differential algorithm management anemia syndrome workup aptt bleeding bruising cardiomyopathy classification clinical coagulation disorders elevatedmcv macrocytic macrocytosis microcytic oncology peripartum
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... e.g. ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Increased Requirement (e.g ... Liver Function Tests ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... • Secondary (e.g ... #Algorithm #Causes ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Differential #Diagnosis ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac ... Paraneoplastic (e.g ... ), TEMPI (VEGF normal ... #Algorithm #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Differential Diagnosis ... Iron Deficiency (Eg ... Other • e.g ... #Differential #Diagnosis ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Destruction • Abnormal ... Rare • Drugs (e.g ... #Hematology
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
thromboembolism → Cardiac ... Vascular imaging → Test ... • Provoked (e.g ... Hypercoagulable #Workup #hematology ... #hematology #VTE
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... thyroid function test ... , ANA (e.g., SLE ... #hematology
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