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Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... VLDL Production/Secretion ... sequestration #pathophysiology
Unmeasured Anions Associated with an Elevated Anion Gap and Metabolic Acidosis

#Unmeasured #Anions #Gap #Metabolic #Acidosis #Diagnosis
Unmeasured Anions ... with an Elevated Anion ... #Unmeasured #Anions ... Diagnosis #Nephrology #Table ... #Differential #Causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Metabolic Acidosis Causes ... and chronic) Causes ... ketosis with ketone excretion ... Cation exchange
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... cells - ↑ Renin secretion ... adrenergic #receptors #actions ... #pharmacology #pathophysiology ... #comparison #table
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Shock #Shock #Pathophysiology ... differential #diagnosis #algorithm ... #causes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
organic acids and bases ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... #Tubules #Table
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... antidiuretic hormone secretion ... Differential #Diagnosis #Algorithm ... #Causes #nephrology
Treatment of Stable Narrow-Complex Tachycardia
Regular Rhythm:
 • Attempt vagal maneuvers
 • Give adenosine 6 milligrams IV
Treatment of Stable ... B-blockers with caution ... Treat underlying cause ... Treat underlying cause ... management #cardiology #algorithm
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
and increased excretion ... AngiotensinII #Pathophysiology ... #Action