Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 β€’ Mechanism: IgG and Complement-mediated
 β€’ Etiology:
Cold Autoimmune Hemolytic ... Spherocytes β€’ Treatment ... β€’ Treatment: Warm ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Extravascular #Causes ... #differential #diagnosis ... #hematology #anemia
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 β€’ Membrane
 β€’ Internal
    - Hemoglobin
Causes of Hemolytic ... - Differential Diagnosis ... Sophia_Hayes_MD #Hemolytic ... #Differential #Diagnosis ... #Causes #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 β€’ Anemia: macrocytic > normocytic, ↑ reticulocytes
 β€’
Anemia 1) DIAGNOSE ... 2) LOOK FOR a cause ... #Anemia #diagnosis ... #management #treatment ... #rheumatology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   β€’ Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... Steroids - 1-2 mg/kg ... #Anemia #AIHA #Treatment ... #management #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... iron deficiency, hemolysis ... inflammatory disorders (e.g ... #Causes #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 β€’ Enzyme deficiencies ex. G6PD, pyruvate kinase 
 β€’ Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... udaygulati #Hemolytic ... #Differential #Diagnosis ... #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
infiltration (e.g ... Retroperitoneal, Uterine β€’ Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #differential #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
defects. 1) HELLP (Hemolysis ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison