Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
(MD) - Diagnosis ... cytopenias (usually anemia ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5. ... Acquired Aplastic Anemia ... β€’ Hypoplastic MDS ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5 ... Acquired Aplastic Anemia ... β€’ Hypoplastic MDS ... #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 β€’ Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... crisis β€’ Severe B12 ... macroangiopathic hemolytic anemia ... " β€’ HELLP syndrome ... #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Malaria, babesia - Nutritional ... : B12, copper, folate ... infection (TB), MDS ... antiphospholipid syndrome ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 β€’ Anemia: macrocytic > normocytic, ↑ reticulocytes
 β€’
1) DIAGNOSE AIHA ... β€’ Anemia: macrocytic ... β€’ Blood smear: Differential ... #diagnosis #management ... #treatment #rheumatology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 β€’ Iron deficiency
Diagnostic Framework ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 β€’ Recurrent infections from neutropenia
 β€’ Mucosal bleeding from
Diagnosis: β€’ Pancytopenia ... Treatment: β€’ Consider ... Can progress to MDS ... #diagnosis #management ... #treatment #hematology
Prevention and Treatment of Nutritional Complications after Bariatric Surgery
Types of Bariatric Surgery:
 β€’ Adjustable Gastric Banding
of Nutritional ... ) Management of ... Surgery: β€’ Dumping Syndrome ... Bariatric #Surgery #Diagnosis ... #Differential #
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 β€’ Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
ataxia), Korsakoff syndrome ... β€’ Vitamin B12 ... Bypass #vitamin #nutrition ... #table #differential ... #diagnosis #bariatric