Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 β€’ Mechanism: IgG and Complement-mediated
 β€’ Etiology:
Anemia Warm Autoimmune ... Hemolytic Anemia ... Anemia: β€’ Mechanism ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... microangiopathy: Thrombotic thrombocytopenic ... #differential #diagnosis ... #hematology #anemia
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 β€’ Anemia: macrocytic > normocytic, ↑ reticulocytes
 β€’
Anemia 1) DIAGNOSE ... AIHA β€’ Anemia ... #Anemia #diagnosis ... #management #treatment ... #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Systemic Lupus Erythematosus ... (<1000/MM3) - THROMBOCYTOPENIA ... anemia #Diagnosis ... #Rheumatology #
Red Blood Cell (RBC) Morphology Atlas
 β€’ Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... Thrombotic idiopathic thrombocytopenia ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 β€’ Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Schistocytes, thrombocytopenia ... #Anemia #Differential ... #workup #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... #differential #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 β€’ Constitutional domain: Fever
 β€’ Cutaneous domain: Non-scarring
Systemic Lupus Erythematosus ... pericarditis β€’ Hematologic ... domain: Leukopenia, Thrombocytopenia ... , Autoimmune hemolysis ... #diagnosis #rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... defects. 1) HELLP (Hemolysis ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... defects. 1) HELLP (Hemolysis ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison