The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
instability - Suicide ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #AMSUICIDE
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Complications Signs ... GiantCell #Temporal #Arteritis ... Complications #Signs ... #Symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... GiantCell #Temporal #Arteritis ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... thoughts of death or suicide ... MoodDisorders #Diagnosis ... Pathophysiology #Signs
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Psoriatic Arthritis ... Arthritis of DIP ... Arthritis mutilans ... pathophysiology #diagnosis ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... pathophysiology #signs ... #symptoms #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... weight-bear • Arthritic ... Fractures #msk #diagnosis ... pathophysiology #signs
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... : - Coronary Arteritis ... #Signs #Symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... erythematosus (SLE) Signs ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... pathophysiology #diagnosis ... #signs #symptoms