The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis psychiatry behavioraldisorder gh growthhormone mnemonic pituitary 21hydroxylasedeficiency 21ohd acute adhd aspd attentiondeficithyperactivedisorder cecs chronicexertional compartmentsyndrome complications conduct corrupt depression
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
auto-reactive B and CD ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
>18 years old, criteria ... not be met for antisocial ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... suicide Other Symptoms ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings Work & lnterpersonal: • Home Life Troubles - Conflict
Antisocial Personality ... disorder #ASPD #Antisocial ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
have either 26 symptoms ... 2 settings - Symptoms ... BehavioralDisorder #Pathophysiology ... #signs #psychiatry ... #criteria
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
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