The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms orthopedics systemic allergic allergy ankylosingspondylitis definitions femoralhead gastrointestinal grades grading gustiloanderson hypersensitivity manifestations mucocutaneous musculoskeletal open pagetsdisease
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... #SLE #MSK #Musculoskeletal ... #Complications ... signs #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... #Erythematosus ... #SLE #Gastrointestinal ... #Complications ... signs #symptoms #diagnosis
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Classification of ... and Complications ... #Classification ... #Orthopedics #MSK ... #diagnosis #complications
Open Fractures: Mechanisms, Clinical Features and Complications Gustilo-Anderson Classification: • Type I - Wound <
and Complications ... Gustilo-Anderson Classification ... #Open #Fractures ... #Diagnosis #Complications ... #MSK #Orthopedics
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Signs/Symptoms/Complications ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... #SLE #Mucocutaneous ... pathophysiology #diagnosis ... signs #symptoms #complications
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
• Ex: Systemic Lupus ... Erythematosus, ... Reactions #Types #Classification ... #Diagnosis #Definitions
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus ( ... SLE) Signs / Symptoms ... Pathophysiology #Diagnosis
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
pseudo-widening in Sl ... column) • Late complication ... bamboo spine) -> Fracture ... pathophysiology #diagnosis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis ... signs #symptoms #complications
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