The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology symptoms msk erythematosus systemic ankylosingspondylitis causes endocrinology excess femoralhead gait gastrointestinal genetics gh giantcell growthhormone manifestations mucocutaneous musculoskeletal
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
(SLE): Musculoskeletal ... - Arthralgia, Arthritis ... Esp. humeral and femoral ... Musculoskeletal #Complications ... pathophysiology #signs
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... pathophysiology #signs
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
) Arteritis: Clinical ... findings and Complications ... Signs/Symptoms ... #Arteritis #Complications ... #Signs #Symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... Erythematosus #SLE ... Gastrointestinal #Complications ... pathophysiology #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... RA) or systemic lupus ... erythematosus (SLE ... ) Signs / Symptoms ... Pathophysiology #Diagnosis #Signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... #SLE #Mucocutaneous ... pathophysiology #diagnosis #signs ... #symptoms #complications
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... /Complications: ... Incr Skeletal fractures
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
of the Hip • Arthritis ... Slipped capital femoral ... Greater Trochanter Fracture ... causes #symptoms #signs
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
pseudo-widening in Sl ... column) • Late complication ... bamboo spine) -> Fracture ... pathophysiology #diagnosis #signs
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
visual acuity • Bitemporal ... Carpal Tunnel Syndrome ... Acne • Coarse features ... Overproduction #diagnosis #signs
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