The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Systemic #Lupus ... pathophysiology #signs ... #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... Pathophysiology #Diagnosis ... #Signs #Symptoms ... #Vasculitis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Complications Signs ... /Symptoms: - ... Complications #Signs ... #Symptoms #diagnosis ... #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... pathophysiology #signs ... #symptoms #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
ObsessiveCompulsive #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Signs #Symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
RA) or systemic lupus ... erythematosus (SLE) Signs ... / Symptoms: - ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
the above with symptoms ... BPD #Borderline #PersonalityDisorder ... #Diagnosis #Psychiatry ... #Criteria #Signs ... #Symptoms #Mnemonic
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Leukocytoclastic vasculitis ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis ... #Signs #Symptoms