The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology vasculitis msk complications temporal disease endocrinology giantcell orthopedics psoriaticarthritis ra rheumatoidarthritis 21hydroxylasedeficiency acute affectivedisorder bakerscyst benign bph causes chondrocalcinosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Cell (Temporal) Arteritis ... Complications Signs ... GiantCell #Temporal #Arteritis ... Complications #Signs ... #Symptoms #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... the etiology Signs ... /Symptoms: - Pretibial ... endocrinology #symptoms ... #signs #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... /Symptoms: - Fever ... Pathophysiology #Diagnosis ... #Signs #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... Fractures #msk #diagnosis ... pathophysiology #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
like rheumatoid arthritis ... erythematosus (SLE) Signs ... / Symptoms: - ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Arthralgia, Arthritis ... pathophysiology #signs ... #symptoms #diagnosis
Psoriatic Arthritis: Pathogenesis and Clinical findings In tendons and connective tissues: • Enthesitis - Pain/tenderness over
Psoriatic Arthritis ... Arthritis of DIP ... Arthritis mutilans ... pathophysiology #diagnosis ... #signs #symptoms
Reactive Arthritis • Inflammation of joints (commonly large joints) - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... pathophysiology #diagnosis ... #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic Hyperplasia ... Benign #Prostatic #Hyperplasia ... Pathophysiology #Urology ... #Signs #Symptoms ... #Diagnosis
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