The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs diagnosis complications arteritis erythematosus temporal allergy gastrointestinal hypersensitivityreaction immunology manifestations msk mucocutaneous musculoskeletal primary sjogrens syndrome takayasus type3
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Lupus #Erythematosus ... #SLE #Gastrointestinal ... pathophysiology #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Osteoporosis #Systemic ... #Lupus #Erythematosus ... pathophysiology #signs #symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... palpation - Vasculitic ... neurological findings #GiantCell ... Diagnosis #Signs #Symptoms ... #Vasculitis
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... (SLE): Pathogenesis ... Multiple immune system ... #Lupus #Erythematosus ... #SLE #Pathophysiology
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Complications Signs/Symptoms ... Stroke or TIA-like symptoms ... Hemorrhages #GiantCell ... Complications #Signs #Symptoms ... #diagnosis #Vasculitis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... arthritis (RA) or systemic ... lupus erythematosus ... (SLE) Signs / ... Symptoms: - Lymphocyte
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... Livedo Reticularis, Vasculitis ... #SLE #Mucocutaneous ... diagnosis #signs #symptoms
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
the cause: • Systemic ... Lupus • Erythematosus ... (SLE) If bacterial
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
usual defense system ... bacteriuria or cystitis (see ... Pathophysiology #Signs #Symptoms
Takayasu’s Arteritis: Pathogenesis and clinical findings - Fatigue, weight loss, low grade fever, arthralgias - Incr
Syndrome - >10mmHg systolic ... commonly carotid) - Systemic ... Takayasus #Arteritis #Vasculitis ... Diagnosis #Signs #Symptoms
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