Pathnologic @pathnologic
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Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV
KyleBradleyMD "Pattern ... infection) - "Pattern ... phase between pattern ... #Pathology #Microscopy ... #LymphNode #Clinical
Here is a lymph node with florid follicular hyperplasia typical of HIV lymphadenitis (so-called "pattern A",
lymphadenitis (so-called "pattern ... KyleBradleyMD "Pattern ... Lymphadenitis #PatternA ... #Pathology #Microscopy ... #LymphNode #Clinical
Herpes Simplex Virus 
Lymphadenitis 
 • Expanded paracortex 
 • HSV-infected cells are 
present in areas
• HSV-infected cells ... HSV #Pathology #Microscopy ... #Clinical #LymphNode
Paracoccidioides brasiliensis Lymphadenitis: 

Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in
fibrosis (A) and well-formed ... seen within giant cells ... Lymphadenitis #Pathology #LymphNode ... #Clinical #Microscopy
Tinea Versicolor - Physical examination revealed large, coalescing, hypopigmented patches and macules on her torso and
and meatball” pattern ... #Clinical #Derm ... TineaVersicolor #Rash #Microscopy
Signet ring cell histiocytes in lymph node sinuses! This can mimic metastatic adenocarcinoma. Histiocytes have ingested
Signet ring cell ... #SignetRing #Cell ... #Histiocytes #LymphNode ... #Pathology #Clinical ... #Microscopy
Hobnail variant of PTC: micropapillary architecture, dense eosinophilic cytoplasm, hobnail cells with apical nuclei, and marked
cytoplasm, hobnail cells ... PTC #Papillary #Thyroid ... Carcinoma #Pathology #Clinical ... #Microscopy
Amiodarone induced thyroid changes

Histopath: Remarkably enlarged follicles, distended with colloid, without 
scalloping, and lined by flattened
Amiodarone induced thyroid ... flattened follicular cells ... change, Follicular cells ... AIT #Pathology #Clinical ... #Microscopy
Salivary acinic cell carcinoma is usually an H&E diagnosis for me- but this zymogen-granule poor variant
Salivary acinic cell ... characteristic staining pattern ... Salivary #Acinic #Cell ... Carcinoma #Pathology #Microscopy ... #Clinical
Diffuse Sclerosis Variant—PTC 
 - Rare variant of PTC 
 - Approximately 3% ofall PTC
Diffuse Sclerosis ... • Carcinoma cells ... PTC #Papillary #Thyroid ... Cancer #Pathology #Clinical ... #Gross #Microscopy