45 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... Anti-cardiolipin (aCl ... LAC) • Sjogren Syndrome ... #diagnosis #associations
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... - Autoimmune: SLE ... antiphospholipid syndrome ... #Framework #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... not required in all ... #Differential #Diagnosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP Syndrome ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Associated - SLE
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
least 2 joints • Neurologic ... pericarditis • Hematologic ... domain: Leukopenia, Thrombocytopenia ... Classification #Criteria #SLE ... Erythematosus #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... signs #symptoms #diagnosis ... #rheumatology