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diagnosis rheumatology differential erythematosus lupus management causes classification signs symptoms thrombocytopenia activation ana anca antibodies antibody antineutrophil antinuclear aortitis associations
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... Thrombocytopenia #Lupus #SLE ... symptoms #diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Causes #Hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
- SLE Neurologic ... system • Entrapment ... Lyme disease, Vasculitis ... Genitourinary system ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... diseases: - 10% SLE ... disorder (e.g. systemic ... erythematosus (SLE ... classification #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Criteria - Systemic ... SEROSITIS - RENAL - NEUROLOGIC ... #Diagnosis #Rheumatology ... #SLE #Lupus #Erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... • Scleroderma (Systemic ... Polymerase Ill • ANCA Vasculitis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria ... for Systemic Lupus ... least 2 joints • Neurologic ... Classification #Criteria ... #SLE #Systemic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... in drug-induced SLE ... ) • Systemic sclerosis ... cases • Sjögren syndrome ... ANCA-Associated Vasculitis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... arteritis, Cogan's Syndrome ... ANCA associated vasculitis ... Arthritis (RA), Systemic ... erythematosus (SLE
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