25 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... inflammation (SLE ... annulus valve: ... Regurgitation #differential ... #diagnosis #cardiology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fever (50%), Depression ... Pericarditis, Endocarditis ... , Aortic valve lesions ... Abdominal pain ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Subacute bacterial endocarditis ... - Bacterial endocarditis ... #differential # ... diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... ; sometimes « viral ... 9) Unexplained fever ... #diagnosis #sle ... erythematosus #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Diagnosis Algorithm ... Autoimmune: • SLE ... • Infectious endocarditis ... #causes
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Autoimmune: SLE ... - Mechanical: valve ... replacement, endocarditis ... #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... lesions • Discoid lupus ... dermatology #joint #pain ... #skin #rashes #differential ... #diagnosis #rheumatology
Causes of mitral stenosis
Rheumatic heart disease
 - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... leaflets/chordae) - SLE ... disease Infective endocarditis ... atrial myxoma)/ball valve ... #diagnosis #differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis
Acute:
 • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Causes of Severe ... Diagnosis Acute ... , Rheumatic Fever ... Inflammatory: Lupus ... #Diagnosis #Causes
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Marantic (NTBE) Differential ... #Endocarditis #diagnosis