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management lupus erythematosus antinuclear hematology symptoms workup algorithm patterns antibodies antibody neurology table aptt autoantibodies bruising cardiology coagulation comparison disorders
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... scleroderma (SSc) • Nucleolar ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies (ANA ... ) ANA or Anti-NucIear ... antigens in the nucleus ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
• Reticular/AMA ... PBC/SjS OS - AMA ... ARUPConsult @ARUPLabs #ANA ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... - CRP: Usually normal ... Workup: - ANA ... Management #Summary #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... ANA (anti-nuclear ... • Scleroderma (Systemic ... #diagnosis #associations
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... Destruction • Abnormal ... ASA) • Renal Disease ... #Causes #Hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... autoantibodies #signs ... #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Myopathy (Also caused ... pathophysiology #signs ... #symptoms #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Differential Diagnosis ... investigations abnormal ... signs • Glomerulonephritis ... , ANA, Anti-GBM, ... #causes
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... pericarditis (search ANA ... pleurisy (search ANA ... cytopenia (search ANA ... #sle #clues #system
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