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differential management algorithm oncology syndrome comparison dermatology disorders pruritus secondary systemic thrombocytopenia thrombocytosis workup aplastic chronic cll generalized hemeonc hemolytic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Chronic Myelogenous Leukemia ... effect following treatment ... Iron deficiency anemia ... #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... Non-infectious (malignancy, rheumatologic ... Chronic Myeloid Leukemia ... #causes #Platelets ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... (CBC with Lymphocytes ... #Algorithm #Causes ... #Hematology #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Treatment: • Consider ... to MDS or acute leukemia ... #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... #MCV #Classification ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... malignancies • Anemia ... Chronic myeloid leukemia ... #Causes #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... • Anemia: macrocytic ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... #Hemolytic #Anemia ... #causes #classification ... #hematology
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