47 results
diagnosis hematology differential management algorithm causes lupus systemic erythematosus monoclonal skin clinical mgus myelodysplastic vasculitis anemia chronic cutaneous doac gammopathy
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... dermatomyositis, SLE ... myelodysplastic #syndrome ... differential #diagnosis #dermatology ... #oncology #clinical
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
severe disease & renal ... block • Sjogren syndrome ... polymyositis overlap syndrome ... • Specific for SLE ... Summary #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... IBD • RA • SLE ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Infectious: • Dental ... Autoimmune: • SLE ... • Sjogren's syndrome ... Preeclampsia Dermatologic ... • Nephrotic syndrome
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Special cases (e.g. renal ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
capillary leak syndrome ... • Schnitzler syndrome ... Cryoglobulinemia Renal-centered ... Differential #Diagnosis #hematology ... #oncology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolytic-uremic syndrome ... • Scleroderma renal ... anemia" • HELLP syndrome ... differential #diagnosis #hematology
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